What is the catalog number for CD74 Antibody?

The catalog number for CD74 Antibody is orb2641953.

What sizes are available for CD74 Antibody?

CD74 Antibody is available in the following size(s): 7 mL.

Is CD74 Antibody in stock?

CD74 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CD74 Antibody

CD74 associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [RefSeq]

Product Specifications

UniProt

P04233

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the CD74 antibody. The epitope is known to be extracellular.

Clonality

Monoclonal

Clone

CDLA74-1

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation; Cell Biology

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Titering of the CD74 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.