What is the catalog number for VCAM-1 Antibody?

The catalog number for VCAM-1 Antibody is orb2641893.

What sizes are available for VCAM-1 Antibody?

VCAM-1 Antibody is available in the following size(s): 7 mL.

Is VCAM-1 Antibody in stock?

VCAM-1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

VCAM-1 Antibody

Vascular cell adhesion molecule-1 (VCAM-1), also called L1CAM and CD106, is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [UniProt]

Product Specifications

UniProt

P19320

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the VCAM-1 antibody.

Clonality

Monoclonal

Clone

CDLA106

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Titering of the VCAM-1 antibody may be required for optimal performance.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.