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CD21 Antibody

CD21/CR2 is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. This mAb is highly specific to CR2 and shows no cross-reaction with CR1.

Product Specifications

UniProt

P20023

Reactivity

Human

Immunogen

A portion of amino acids 44-196 were used as the immunogen for the CD21 antibody.

Clonality

Monoclonal

Clone

CDLA21-1

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CD21 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Tested Applications

IHC-P

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG1, kappa

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