(±) -Epibatidine (dihydrochloride)
(±) -Epibatidine (CMI 545) dihydrochloride is an agonist of nicotinic with potent analgetic activity. (±) -Epibatidine (CMI 545) dihydrochloride is an alkaloid originally characterized from frog skin. (±) -Epibatidine (CMI 545) dihydrochloride have little or no activity at a variety of other central receptors, including opioid receptors, muscarinic receptors, adrenergic receptors, dopamine receptors, serotonin receptors, and gamma-aminobutyric acid receptors[1].
Product Specifications
CAS Number
[162885-01-0]
Product Name Alternative
CMI 545 (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Dopamine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-epibatidine-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C([C@H]2[C@@H](N3)CC[C@@H]3C2)C=N1.[H]Cl.[H]Cl
Molecular Formula
C11H15Cl3N2
Molecular Weight
281.61
Precautions
P261-P280-P302+P352
References & Citations
[1]Badio B, et al. Epibatidine, a potent analgetic and nicotinic agonist. Mol Pharmacol. 1994;45 (4) :563-569.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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