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(±) -Epibatidine (dihydrochloride)

(±) -Epibatidine (CMI 545) dihydrochloride is an agonist of nicotinic with potent analgetic activity. (±) -Epibatidine (CMI 545) dihydrochloride is an alkaloid originally characterized from frog skin. (±) -Epibatidine (CMI 545) dihydrochloride have little or no activity at a variety of other central receptors, including opioid receptors, muscarinic receptors, adrenergic receptors, dopamine receptors, serotonin receptors, and gamma-aminobutyric acid receptors[1].

Product Specifications

CAS Number

[162885-01-0]

Product Name Alternative

CMI 545 (dihydrochloride)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Dopamine Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/racemic-epibatidine-dihydrochloride.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C([C@H]2[C@@H](N3)CC[C@@H]3C2)C=N1.[H]Cl.[H]Cl

Molecular Formula

C11H15Cl3N2

Molecular Weight

281.61

Precautions

P261-P280-P302+P352

References & Citations

[1]Badio B, et al. Epibatidine, a potent analgetic and nicotinic agonist. Mol Pharmacol. 1994;45 (4) :563-569.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

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