What is the catalog number for Recombinant NKX2.2 Antibody?

The catalog number for Recombinant NKX2.2 Antibody is orb2640834.

What sizes are available for Recombinant NKX2.2 Antibody?

Recombinant NKX2.2 Antibody is available in the following size(s): 7 mL.

Is Recombinant NKX2.2 Antibody in stock?

Recombinant NKX2.2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant NKX2.2 Antibody

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Product Specifications

UniProt

O95096

Reactivity

Human

Immunogen

Human recombinant protein was used as the immunogen for this recombinant NKX2.2 antibody.

Clonality

Recombinant

Clone

RNX2/1523

Conjugation

Unconjugated

Field of Research

Stem Cell & Developmental Biology

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant NKX2.2 antibody to be titered up or down for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.