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Recombinant Human Growth/Differentiation Factor 15 / Macrophage Inhibitory Cytokine 1

Product Specifications

Target

Ala197-Ile308; Accession # Q99988

Purification

> 95 % by SDS-PAGE analyses.

Endotoxin

Less than 0.1 EU/ug of rHuGDF-15/MIC-1 as determined by LAL method.

Bioactivity

Measured by its binding ability in a functional ELISA. When rHuGDF-15/MIC-1 is used at 0.5 μg/mL, the concentration of Recombinant Human Activin RIB/ALK-4 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-3 μg/mL.

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculated Molecular Weight

Predicted molecular mass of approximately 12 kDa in SDS-PAGE under reducing condition.

Formulation

Lyophilized from 0.2 μm filtered concentrated solution in 4 mM HCl.

Host or Source

Escherichia coli

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