What is the catalog number for Caldesmon Antibody / CALD1 / CAD (HMW)?

The catalog number for Caldesmon Antibody / CALD1 / CAD (HMW) is orb2639376.

What sizes are available for Caldesmon Antibody / CALD1 / CAD (HMW)?

Caldesmon Antibody / CALD1 / CAD (HMW) is available in the following size(s): 7 mL.

Is Caldesmon Antibody / CALD1 / CAD (HMW) in stock?

Caldesmon Antibody / CALD1 / CAD (HMW) is currently made to order / not held in immediate stock. Contact us for lead time.

Caldesmon Antibody / CALD1 / CAD (HMW)

Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

Product Specifications

UniProt

Q05682

Reactivity

Human

Immunogen

Crude human uterus extract was used as the immunogen for the Caldesmon antibody.

Clonality

Monoclonal

Clone

SPM168

Conjugation

Unconjugated

Field of Research

Musculoskeletal & Connective Tissue Research

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the Caldesmon antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.