TRP1 Antibody / Tyrosinase-Related Protein-1 Antibody / TYRP1
Selected Variant
GTR18572823
Size: 100 µg
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Product Specifications
UniProt
P17643
Reactivity
Human, Mouse
Immunogen
Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.
Clonality
Monoclonal
Clone
SPM611
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 2-4ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2a, kappa
Price
Frequently Asked Questions
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