Gp96 Antibody / GRP94 / HSP90B1
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96) . Gp96 shows a high degree of sequence homology with the heat shock protein 90 (hsp90) . This mAb is highly specific and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Gp96 has been briefly studied as a prognostic factor in breast cancer.
Product Specifications
UniProt
P14625
Reactivity
Human
Immunogen
Purified glucose regulated protein 94 from chicken oviducts was used as the immunogen for the gp96 antibody.
Clonality
Monoclonal
Clone
SPM249
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
FACS, IF, IHC-P
Host or Source
Rat
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rat IgG2a, kappa
Frequently Asked Questions
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