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TIBI

TIBI is a potent and ATP-competitive inhibitor of Rio1 (IC50: 0.09 μM, Ki: 0.05 μM) . TIBI enhances the thermostability of the enzyme Rio1[1].

Product Specifications

CAS Number

1196457-06-3

UNSPSC

12352005

Target

Ser/Thr Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tibi.html

Purity

99.62

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

IC1=C2C(N=CN2)=C(C(I)=C1I)I

Molecular Formula

C7H2I4N2

Molecular Weight

621.72

References & Citations

[1]Kubiński K, et al. Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. Mol Cell Biochem. 2017 Feb;426 (1-2) :195-203.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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