TIBI
TIBI is a potent and ATP-competitive inhibitor of Rio1 (IC50: 0.09 μM, Ki: 0.05 μM) . TIBI enhances the thermostability of the enzyme Rio1[1].
Product Specifications
CAS Number
1196457-06-3
UNSPSC
12352005
Target
Ser/Thr Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tibi.html
Purity
99.62
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
IC1=C2C(N=CN2)=C(C(I)=C1I)I
Molecular Formula
C7H2I4N2
Molecular Weight
621.72
References & Citations
[1]Kubiński K, et al. Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. Mol Cell Biochem. 2017 Feb;426 (1-2) :195-203.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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