What is the catalog number for PD-1 Antibody?

The catalog number for PD-1 Antibody is orb2639049.

What sizes are available for PD-1 Antibody?

PD-1 Antibody is available in the following size(s): 100 µg.

Is PD-1 Antibody in stock?

PD-1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PD-1 Antibody

PDCD-1 (programmed cell death-1 protein), also called PD-1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Product Specifications

UniProt

Q15116

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the PD-1 antibody.

Clonality

Monoclonal

Clone

PDCD1/922

Conjugation

Unconjugated

Field of Research

Cancer Biology

Purification

Protein G affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the PD-1 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.