Ornithine Decarboxylase Antibody
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1) . ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
Product Specifications
UniProt
P11926
Reactivity
Human, Rat
Immunogen
Recombinant human protein was used as the immunogen for the Ornithine Decarboxylase antibody.
Clonality
Monoclonal
Clone
ODC1/487
Conjugation
Unconjugated
Field of Research
Pharmacology & Drug Discovery
Purification
Protein G affinity chromatography
Dilution
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
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