What is the catalog number for AR Antibody / Androgen Receptor?

The catalog number for AR Antibody / Androgen Receptor is orb2638686.

What sizes are available for AR Antibody / Androgen Receptor?

AR Antibody / Androgen Receptor is available in the following size(s): 7 mL.

Is AR Antibody / Androgen Receptor in stock?

AR Antibody / Androgen Receptor is currently made to order / not held in immediate stock. Contact us for lead time.

AR Antibody / Androgen Receptor

Recognizes a protein of 100kDa, which is identified as androgen receptor (AR) . It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This mAb is superb for staining of formalin/paraffin tissues.

Product Specifications

UniProt

P10275

Reactivity

Human

Immunogen

Amino acids 302-318 (STEDTAEYSPFKGGYTK) from human Androgen Receptor were used as the immunogen for the AR antibody.

Clonality

Monoclonal

Clone

AR441

Conjugation

Unconjugated

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the AR antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.