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Mito-TRFS

Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells[1].

Product Specifications

CAS Number

[1859102-62-7]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mito-trfs.html

Purity

99.11

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=C(NC(OC2CSSC2)=O)C3=CC=CC4=C13)N(CCOCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)C4=O.[I-]

Molecular Formula

C38H34IN2O5PS2

Molecular Weight

820.70

References & Citations

[1]Yaping Liu, et al. A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model. Chem Commun (Camb) . 2016 Feb 7;52 (11) :2296-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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