CD48 Antibody (Pan Leukocyte Marker)
Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI) -anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
Product Specifications
UniProt
P09326
Reactivity
Human
Immunogen
A portion of amino acids 59-178 was used as the immunogen for the CD48 antibody.
Clonality
Monoclonal
Clone
CD48/4784
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Western blot: 2-4ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD48 antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2c, kappa
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