Aladorian (sodium)

Aladorian (ARM036) sodium is a benzothiazepine derivative, with anti-arrhythmia effect. Aladorian sodium is a ryanodine receptor (RyR2) blocker. Aladorian sodium is used for the research of heart failure and catecholaminergic polymorphic ventricular tachycardia[1][2][3].

Product Specifications

CAS Number

[1233219-11-8]

Product Name Alternative

ARM036 (sodium)

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/aladorian-sodium.html

Smiles

O=C(C(N1CCSC2=CC=C(C=C2C1)OC)=O)O[Na]

Molecular Formula

C12H12NNaO4S

Molecular Weight

289.28

References & Citations

[1]Thevis M, et al. Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls. J Pharm Biomed Anal. 2014 Dec;101:66-83.|[2]Luo M, et al. Mechanisms of altered Ca²⁺ handling in heart failure. Circ Res. 2013 Aug 30;113 (6) :690-708.|[3]Kupatt C, et al. Ryanodine Receptors Matter for Cardiac Function in Duchenne Muscular Dystrophy: Stability First. J Am Coll Cardiol. 2021 Dec 14;78 (24) :2454-2456.