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Recombinant IGL Antibody / Lambda Light Chain

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Product Specifications

UniProt

P01701, P01842

Reactivity

Human

Immunogen

Recombinant full-length human Lambda light chain protein was used as the immunogen for the recombinant IGL antibody.

Clonality

Recombinant

Clone

IGL/3886R

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein A/G affinity

Dilution

ELISA

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the recombinant IGL antibody should be determined by the researcher.

Tested Applications

ELISA

Host or Source

Rabbit

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide

Isotype

Rabbit IgG, kappa

Available Sizes

Frequently Asked Questions

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