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S100A4 Antibody / FSP1

S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, a6b4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.

Product Specifications

UniProt

P26447

Reactivity

Human

Immunogen

A recombinant fragment (within amino acids 1-101) of human S100A4 protein was used as the immunogen for the S100A4 antibody.

Clonality

Monoclonal

Clone

S100A4/6799

Conjugation

Unconjugated

Field of Research

Signal Transduction

Purification

Protein A/G affinity

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml, Western blot: 2-4ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the S100A4 antibody should be determined by the researcher.

Tested Applications

IHC-P, WB

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG1, kappa

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