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Recombinant Carbonic Anhydrase IX Antibody / CA9

CAIX is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, CAIX is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Product Specifications

UniProt

Q16790

Reactivity

Human

Immunogen

The extracellular N-terminal proteoglycan-like region was used as the immunogen for the recombinant Carbonic Anhydrase IX antibody.

Clonality

Recombinant

Clone

CA9/9621R

Conjugation

Unconjugated

Purification

Protein A/G affinity

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml, Western blot: 2-4ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the recombinant Carbonic Anhydrase IX antibody should be determined by the researcher.

Tested Applications

IHC-P, WB

Host or Source

Rabbit

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Rabbit IgG, kappa

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