Human CXCL3 Protein, His tag (Animal-Free)

C-X-C motif chemokine 3 (CXCL3) also named Growth-regulated oncogene gamma (GROγ), which is a chemokine of the intercrine alpha family. CXCL3 is a 8kDa protein containing 73 amino acid residues. During inflammation, CXCL3 is activated by the TNF and IL-1 which mediates the monocytes migration and adhesion by targeting the CXCR2. CXCL3 activates the JNK activity which induce the cell differentiation.

Product Specifications

Background

Product Name Alternative

GRO-γ: MGSAγ, MIP-2β, GRO3

Gene ID

2921

Accession Number

P19876

Tag

CXCL3

Type

Cytokines and proteins

Applications

His tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measure by its ability to chemoattract BaF3 cells transfected with human CXCR3.The ED₅₀ for this effect is <2 ng/mL.

Molecular Formula

8.67 kDa

Molecular Weight

8.67 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin :< 0.1 EU per μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA,10% FBS or 0.1%BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human CXCL3 consists of 73 amino acids and predicts a molecular mass of 8.67 kDa.

Formulation

Lyophilized from sterile PBS, pH 7.4.

Applications Notes

Human

Other Product Names

CXCL3, CXCL-3, GRO-γ:MGSAγ, MIP-2β, GRO3

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously.