Recombinant SHBG Antibody / Sex Hormone Binding Globulin
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Product Specifications
UniProt
P04278
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the recombinant SHBG antibody.
Clonality
Recombinant
Clone
RSHBG/245
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein A/G affinity
Dilution
ELISA (order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant SHBG antibody should be determined by the researcher.
Tested Applications
ELISA, IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa
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