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BigLEN (rat)

BigLEN (rat) is a potent GPR171 agonist with an EC50 of 1.6 nM[1].

Product Specifications

CAS Number

369377-66-2

UNSPSC

12352209

Target

GPR171

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/biglen-rat.html

Purity

98.98

Solubility

H2O : ≥ 50 mg/mL

Smiles

O=C(N1[C@@H](CCC1)C(O)=O)[C@H]2N(CCC2)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CO)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C76H128N24O23

Molecular Weight

1745.98

References & Citations

[1]Gomes I, et al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013;110 (40) :16211-16216

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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