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CD50 Antibody / ICAM-3

Recognizes the N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.

Product Specifications

UniProt

P32942

Reactivity

Human

Immunogen

Human protein was used as the immunogen for the CD50 antibody.

Clonality

Monoclonal

Clone

ICO-60

Conjugation

Unconjugated

Field of Research

Neuroscience; Immunology & Inflammation

Purification

Protein G affinity chromatography

Dilution

Flow cytometry: 1-2ug/10^6 cells in 0.1ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the CD50 antibody should be determined by the researcher.

Tested Applications

FACS

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG1, kappa

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