Glucose 6-Phosphate Isomerase Antibody / GPI
In addition to it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.
Product Specifications
UniProt
P06744
Reactivity
Human
Immunogen
A recombinant human full-length protein was used as the immunogen for the Glucose 6-Phosphate Isomerase antibody.
Clonality
Monoclonal
Clone
CPTC-GPI-1
Conjugation
Unconjugated
Field of Research
Metabolism Research; Pharmacology & Drug Discovery
Purification
Protein G affinity chromatography
Dilution
Western blot: 1-2ug/ml, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Glucose 6-Phosphate Isomerase antibody should be determined by the researcher.
Tested Applications
IF, IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
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