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Avibactam tomilopil

Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections[1][2][3].

Product Specifications

CAS Number

[2245880-46-8]

Product Name Alternative

ARX-1796; AV-006

UNSPSC

12352005

Target

Bacterial; Beta-lactamase; Drug Intermediate

Type

Reference compound

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/avibactam-tomilopil.html

Purity

98.57

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(OCC(C)(C)C(OCC)=O)(=O)=O)=O)=O

Molecular Formula

C14H23N3O8S

Molecular Weight

393.41

References & Citations

[1]Veeraraghavan B, et al. Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections. Infect Dis Ther. 2021;10 (4) :1815-1835. |[2]Falcone M, et al. Spotlight on ceftazidime/avibactam: a new option for MDR Gram-negative infections. J Antimicrob Chemother. 2016;71 (10) :2713-2722. |[3]Huband MD, et al. Determination of MIC Quality Control Ranges for Ceftibuten-Avibactam (Fixed 4 μg/mL), a Novel β-Lactam/β-Lactamase Inhibitor Combination. J Clin Microbiol. 2023 Jul 20;61 (7) :e0165722.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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