What is the catalog number for NPM Antibody / Nucleophosmin?

The catalog number for NPM Antibody / Nucleophosmin is orb2642972.

What sizes are available for NPM Antibody / Nucleophosmin?

NPM Antibody / Nucleophosmin is available in the following size(s): 7 mL.

Is NPM Antibody / Nucleophosmin in stock?

NPM Antibody / Nucleophosmin is currently made to order / not held in immediate stock. Contact us for lead time.

NPM Antibody / Nucleophosmin

The protein encoded by the NPM1 gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. [RefSeq]

Product Specifications

UniProt

P06748

Reactivity

Human

Immunogen

A portion of amino acids 185-287 from the human protein was used as the immunogen for the NPM antibody.

Clonality

Monoclonal

Clone

NLPP1-1

Conjugation

Unconjugated

Field of Research

Cancer Biology

Purification

Protein G affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the NPM antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.