What is the catalog number for Recombinant SPTBN2 Antibody / Spectrin beta III?

The catalog number for Recombinant SPTBN2 Antibody / Spectrin beta III is orb2642561.

What sizes are available for Recombinant SPTBN2 Antibody / Spectrin beta III?

Recombinant SPTBN2 Antibody / Spectrin beta III is available in the following size(s): 7 mL.

Is Recombinant SPTBN2 Antibody / Spectrin beta III in stock?

Recombinant SPTBN2 Antibody / Spectrin beta III is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant SPTBN2 Antibody / Spectrin beta III

Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1) . SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [RefSeq]

Product Specifications

UniProt

O15020

Reactivity

Human

Immunogen

Amino acids 356-475 from the human protein were used as the immunogen for this recombinant SPTBN2 antibody.

Clonality

Recombinant

Clone

SCNB3-2R

Conjugation

Unconjugated

Field of Research

Neuroscience

Purification

Protein A affinity chromatography

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the recombinant SPTBN2 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.