What is the catalog number for Basic Cytokeratin Antibody?

The catalog number for Basic Cytokeratin Antibody is orb2642432.

What sizes are available for Basic Cytokeratin Antibody?

Basic Cytokeratin Antibody is available in the following size(s): 7 mL.

Is Basic Cytokeratin Antibody in stock?

Basic Cytokeratin Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Basic Cytokeratin Antibody

This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1) ; 64kDa (CK3) ; 59kDa (CK4) ; 58kDa (CK5) ; 56kDa (CK6) ; 52kDa (CK8) . Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Product Specifications

UniProt

Q01546

Reactivity

Human

Immunogen

Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.

Clonality

Monoclonal

Clone

SPM116

Conjugation

Unconjugated

Field of Research

Neuroscience

Purification

Protein G purified

Dilution

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Differences in protocols and secondaries may cause the Basic Cytokeratin antibody to need titering for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.