VU0359595
VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM) . VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases[1][2][3][4].
Product Specifications
CAS Number
1246303-14-9
Product Name Alternative
CID-53361951; ML-270
UNSPSC
12352005
Target
Fungal; Phospholipase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0359595.html
Purity
98.06
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C([C@H]1[C@H](C2=CC=CC=C2)C1)N[C@@H](C)CN3CCC(N4C5=CC=C(Br)C=C5NC4=O)CC3
Molecular Formula
C25H29BrN4O2
Molecular Weight
497.43
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLD
Available Sizes
Frequently Asked Questions
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