VU0359595
VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM) . VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases[1][2][3][4].
Product Specifications
CAS Number
1246303-14-9
Product Name Alternative
CID-53361951; ML-270
UNSPSC
12352005
Target
Fungal; Phospholipase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0359595.html
Purity
98.06
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C([C@H]1[C@H](C2=CC=CC=C2)C1)N[C@@H](C)CN3CCC(N4C5=CC=C(Br)C=C5NC4=O)CC3
Molecular Formula
C25H29BrN4O2
Molecular Weight
497.43
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLD
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Carboxypeptidase Z (CPZ) (NM_003652) Human Over-expression Lysate
