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Recombinant TYRP1 Antibody / Tyrosinase Related Protein 1 / TRP1

Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Product Specifications

UniProt

P17643

Reactivity

Human

Immunogen

Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.

Clonality

Recombinant

Clone

TYRP1/1564R

Conjugation

Unconjugated

Field of Research

Metabolism Research

Purification

Protein A affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.

Tested Applications

IHC-P

Host or Source

Rabbit

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Rabbit IgG, kappa

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