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TCF4 Antibody

Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4) . It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Product Specifications

UniProt

P15884

Reactivity

Human

Immunogen

A portion of amino acids 365-671 from the human protein was used as the immunogen for this TCF4 antibody.

Clonality

Monoclonal

Clone

TCF4/1705

Conjugation

Unconjugated

Purification

Protein G affinity chromatography

Dilution

ELISA: 2-4ug/ml (order BSA/azide-free format), Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the TCF4 antibody should be determined by the researcher.

Tested Applications

ELISA, IHC-P, WB

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG2a, kappa

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