MUC3 Antibody
It recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3) . This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3) . The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
Product Specifications
UniProt
Q02505
Reactivity
Human
Immunogen
Amino acids (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS) which contains two of the MUC3 tandem repeats was used as the immunogen for the MUC3 antibody.
Clonality
Monoclonal
Clone
MUC3/1154
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Anti-PTPN22 Picoband® Antibody Fluoro647 Conjugated
Hck, NT (Hck, Tyrosine-protein kinase HCK, B Cell/myeloid kinase, Hematopoietic cell kinase, Hemopoietic cell kinase, p56-HCK/p59-HCK) (PE) discontinued
EREG, CT (EREG, Proepiregulin, Epiregulin) (AP) discontinued
