C-Met-IN-15
C-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. c-Met-IN-15 inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM[1].
Product Specifications
CAS Number
[330572-32-2]
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-met-in-15.html
Purity
98.50
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)O)N/N=C2C(NC3=CC=C(C=C\23)F)=O
Molecular Formula
C15H10FN3O3
Molecular Weight
299.26
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Liang Z, et, al. Identification and synthesis of N'- (2-oxoindolin-3-ylidene) hydrazide derivatives against c-Met kinase. Bioorg Med Chem Lett. 2011 Jun 15;21 (12) :3749-54.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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