Resorufin methyl ether

Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate[1]. Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents[1][2].

Product Specifications

CAS Number

[5725-89-3]

Product Name Alternative

Methoxyresorufin

UNSPSC

12171500

Target

Cytochrome P450

Type

Dye Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/resorufin-methyl-ether.html

Purity

99.75

Solubility

DMF : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=CC2=NC3=C(C=C(OC)C=C3)OC2=C1

Molecular Formula

C13H9NO3

Molecular Weight

227.22

References & Citations

[1]P V Nerurkar, et al. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem Pharmacol. 1993 Sep 1;46 (5) :933-43.|[2]Hansen Murcia, et al. Study on the inhibitory effect of furafylline and troleandomycin in the 7-methoxyresorufin-O-demethylase and nifedipine oxidase activities in hepatic microsomes from four poultry species using high-performance liquid chromatography coupled with fluorescence and ultraviolet detection. J Pharm Biomed Anal. 2019 Feb 5;164:148-154.