(S)-AMPA
Product Specifications
UNSPSC Description
(S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist[1][2].
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-ampa.html
Purity
99.0
Solubility
H2O : 18.7 mg/mL (ultrasonic;warming)
Smiles
O=C1C(C[C@H](N)C(O)=O)=C(C)ON1
Molecular Weight
186.17
References & Citations
[1]J A Larm, et al. (S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors. Eur J Pharmacol. 1996 Oct 24;314(1-2):249-54.|[2]B Ebert, et al. Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA. Neurochem Int. 1994 Jun;24(6):507-15.|[3]J W Brooks, et al. (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A. Neurosci Lett. 2004 Nov 30;372(1-2):85-8.|[4]J A Larm, et al. Apoptosis induced via AMPA-selective glutamate receptors in cultured murine cortical neurons. J Neurochem. 1997 Aug;69(2):617-22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100815A/S-AMPA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100815A/S-AMPA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
83643-88-3
Available Sizes
Curated Selection
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