Cafestol
Cafestol is an orally active diterpenoid and an inhibitor of ERK2. Cafestol has elevated blood lipids, anti-inflammatory, anti-angiogenic and anti-diabetic activities. In addition, Cafestol induces tumor cell apoptosis and autophagy, which can be used in the study of cancer[1][2][3][4].
Product Specifications
CAS Number
469-83-0
UNSPSC
12352005
Target
AP-1; Apoptosis; Autophagy; COX; ERK; FAK; NF-κB; PGE synthase
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; MAPK/ERK Pathway; NF-κB; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Endocrinology; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cafestol.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C5=C(OC=C5)CC2)C[C@@]([C@](CO)(O)C4)([H])CC3
Molecular Formula
C20H28O3
Molecular Weight
316.43
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; ERK2; NF-κB
Available Sizes
Frequently Asked Questions
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