Sirtuin modulator 1

Sirtuin modulator 1 is a modulator of SIRTl, a homolog of SIRT3, with EC1.5 of < 1 μM, extracted from patent WO 2010071853 A1, Compound No.4.

Product Specifications

CAS Number

[2070015-26-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Sirtuin-modulator-1.html

Purity

99.85

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

O=C(C1=C(CCCOC)SC(C2=CC=CC=C2)=N1)NC3=CC=CC=C3C4=NC5=C(N=CC(CN6CCCC6)=C5)S4.Cl[H]

Molecular Formula

C31H32ClN5O2S2

Molecular Weight

606.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Thiazolopyridine sirtuin modulating compounds. WO 2010071853 A1

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SIRT1

Available Sizes

Curated Selection

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