11-Oxomogroside II A1
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) . 11-Oxomogroside II A1 also weakly inhibits the activation of (±) - (E) -methyl-2-[ (E) -hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor[1].
Product Specifications
CAS Number
942612-74-0
UNSPSC
12352005
Target
EBV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/11-oxomogroside-ii-a1.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@]3([H])[C@]([C@@]4([H])C(C(C)([C@H](CC4)O)C)=CC3)(C(C[C@@]1([C@@](CC2)([H])[C@H](C)CC[C@H](C(C)(O)C)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C)=O)C
Molecular Formula
C42H70O14
Molecular Weight
799.00
References & Citations
[1]Akihisa T, et al. Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation. J Nat Prod. 2007 May;70 (5) :783-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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