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Melengestrol acetate-d6

Melengestrol acetate-d6 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].

Product Specifications

UNSPSC

12352211

Target

Isotope-Labeled Compounds; Progesterone Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Metabolic Disease

Solubility

10 mM in DMSO

Smiles

C[C@]1([C@](C2)([H])[C@]3([H])C=C(C)C4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC1)=O)[C@](C(C([2H])([2H])[2H])=O)(OC(C)=O)C2=C

Molecular Formula

C25H26D6O4

Molecular Weight

402.56

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]G M Padilla, et al. Melengestrol acetate and megestrol acetate are prostatic tumor inhibiting agents. Biochem Cell Biol. 1990 Oct;68 (10) :1181-8.|[3]G W DUNCAN, et al. BIOLOGIC EFFECTS OF MELENGESTROL ACETATE. Fertil Steril. Jul-Aug 1964;15:416-32.|[4]https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/melengestrol-acetate

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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