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SB756050

Product Specifications

UNSPSC Description

SB756050 is a selective TGR5 agonist. SB756050 has the potential for type 2 diabetes treatment.

Target Antigen

G protein-coupled Bile Acid Receptor 1

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/SB756050.html

Purity

98.49

Solubility

DMSO : ≥ 150 mg/mL

Smiles

O=S(N1CCN(S(=O)(C2=CC=C(OC)C(OC)=C2)=O)CCC1)(C3=CC=C(OC)C(OC)=C3)=O

Molecular Weight

500.59

References & Citations

[1]Hodge RJ, et al. Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB-756050, in Type 2 Diabetes. Clin Pharmacol Drug Dev. 2013 Jul;2(3):213-22.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-102016/SB756050-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-102016/SB756050-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

447410-57-3

Available Sizes

Curated Selection

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