SB756050
SB756050 is a selective TGR5 agonist. SB756050 has the potential for type 2 diabetes treatment.
Product Specifications
CAS Number
447410-57-3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
G protein-coupled Bile Acid Receptor 1
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/SB756050.html
Purity
98.89
Solubility
DMSO : ≥ 150 mg/mL
Smiles
O=S(N1CCN(S(=O)(C2=CC=C(OC)C(OC)=C2)=O)CCC1)(C3=CC=C(OC)C(OC)=C3)=O
Molecular Formula
C21H28N2O8S2
Molecular Weight
500.59
Precautions
H315, H319, H335
References & Citations
[1]Hodge RJ, et al. Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB-756050, in Type 2 Diabetes. Clin Pharmacol Drug Dev. 2013 Jul;2 (3) :213-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
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