JC-229
Product Specifications
UNSPSC Description
JC-229 is a TbRPA1 inhibitor. JC-229 targets RPA1 in Trypanosoma brucei. JC-229 can be used for the research of Human African Trypanosomiasis (HAT)[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/jc-229.html
Solubility
DMSO : 40 mg/mL (ultrasonic;adjust pH to 9 with 1M NaOH)
Smiles
O=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=C(C)C(S(=O)(NC3=CC=C(Cl)C(Cl)=C3)=O)=C2
Molecular Weight
504.21
References & Citations
[1]Mukherjee A, et al. Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1. Nat Commun. 2023 Jul 20;14(1):4390.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155655/JC-229-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155655/JC-229-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3026716-22-0
Available Sizes
Curated Selection
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