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LS-75

LS-75 is a PARP-1 inhibitor with blood-brain permeability and IC50 value of 18 μM. LS-75 has neuroprotective activity[1].

Product Specifications

CAS Number

885-70-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PARP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ls-75.html

Purity

99.31

Smiles

O=C1C2=CC=CC=C2NC=3N=CC=CC3N1

Molecular Formula

C12H9N3O

Molecular Weight

211.22

Precautions

H302, H315, H319, H335

References & Citations

[1]André Schrattenholz, et al. Muscarinic antagonists with PARP and SIR modulating activity as agents for inflammatory diseases. US8039464B2.2011-10-18.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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