LS-75
LS-75 is a PARP-1 inhibitor with blood-brain permeability and IC50 value of 18 μM. LS-75 has neuroprotective activity[1].
Product Specifications
CAS Number
[885-70-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ls-75.html
Purity
99.31
Smiles
O=C1C2=CC=CC=C2NC=3N=CC=CC3N1
Molecular Formula
C12H9N3O
Molecular Weight
211.22
Precautions
H302, H315, H319, H335
References & Citations
[1]André Schrattenholz, et al. Muscarinic antagonists with PARP and SIR modulating activity as agents for inflammatory diseases. US8039464B2.2011-10-18.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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