Leonurine
Leonurine is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.
Product Specifications
CAS Number
[24697-74-3]
Product Name Alternative
SCM-198
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Leonurine.html
Purity
99.86
Solubility
DMSO : 30.3 mg/mL (ultrasonic; adjust pH to 3 with 1 M HCl) |H2O : < 0.1 mg/mL
Smiles
O=C(OCCCCNC(N)=N)C1=CC(OC)=C(O)C(OC)=C1
Molecular Formula
C14H21N3O5
Molecular Weight
311.33
Precautions
H315, H319, H335
References & Citations
[1]Jiang T, et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. Cell Physiol Biochem. 2017;43 (4) :1703-1717.|[2]Zhang L, et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway. Biomed Pharmacother. 2018 Dec 7;110:571-581.|[3]Hu ZC, et al. Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. J Cell Physiol. 2018 Nov 11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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