Leonurine
Product Specifications
UNSPSC Description
Leonurine is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.
Target Antigen
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Leonurine.html
Purity
99.64
Solubility
DMSO : 30.3 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCL)|H2O : < 0.1 mg/mL
Smiles
O=C(OCCCCNC(N)=N)C1=CC(OC)=C(O)C(OC)=C1
Molecular Weight
311.33
References & Citations
[1]Jiang T, et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. Cell Physiol Biochem. 2017;43(4):1703-1717.|[2]Zhang L, et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway. Biomed Pharmacother. 2018 Dec 7;110:571-581.|[3]Hu ZC, et al. Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. J Cell Physiol. 2018 Nov 11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0741/Leonurine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0741/Leonurine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
24697-74-3
Available Sizes
Curated Selection
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