SP 600125, negative control
SP 600125, negative control (SPM1) is an alkyl derivative of pyrazoloanthrone, which can be used as a negative control for SP600125 (HY-12041) [1].
Product Specifications
CAS Number
[54642-23-8]
Product Name Alternative
JNK Inhibitor II, negative control
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Autophagy; Ferroptosis; JNK
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; MAPK/ERK Pathway
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sp-600125-negative-control.html
Purity
98.05
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C1C2=C3C(N(C)N=C3C4=CC=CC=C14)=CC=C2
Molecular Formula
C15H10N2O
Molecular Weight
234.26
Precautions
H315, H319, H335
References & Citations
[1]Prasad KD, et al. Alkyl chain substituted 1,9-pyrazoloanthrones exhibit prominent inhibitory effect on c-Jun N-terminal kinase (JNK) . Org Biomol Chem. 2014 Jul 14;12 (26) :4656-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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