Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Gossypin

Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study[1][2][3].

Product Specifications

CAS Number

652-78-8

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Apoptosis; Aurora Kinase; Bcl-2 Family; Caspase; Cryptochrome; NF-κB; PARP; Ribosomal S6 Kinase (RSK)

Type

Natural Products

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gossypin.html

Purity

98.29

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=C(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)C(O)=CC(O)=C13

Molecular Formula

C21H20O13

Molecular Weight

480.38

Precautions

H315, H319, H335

References & Citations

[1]Ajaikumar B Kunnumakkara, et al. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood. 2007 Jun 15;109 (12) :5112-21.|[2]Cheng G, et al. Cardioprotective Effect of Gossypin Against Myocardial Ischemic/Reperfusion in Rats via Alteration of Oxidative Stress, Inflammation and Gut Microbiota. J Inflamm Res. 2022 Mar 5;15:1637-1651.|[3]Wang L, et al. Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2. Phytother Res. 2019 Mar;33 (3) :640-650.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Frozen Tissue Sections, Prostate
CS510315 5x 5 µm

Frozen Tissue Sections, Prostate

Sign In for Pricing
View Details
iNOS Recombinant Rabbit Monoclonal Antibody [PSH03-69]
HA722031 100 µL

iNOS Recombinant Rabbit Monoclonal Antibody [PSH03-69]

Sign In for Pricing
View Details
Nudt11 (NM_021431) Mouse Tagged ORF Clone
MG201319 10 µg

Nudt11 (NM_021431) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
CD45RA (PTPRC/818), 0.2mg/mL
BNUB0818-100 1x 100 µL

CD45RA (PTPRC/818), 0.2mg/mL

Sign In for Pricing
View Details
Slc26a7 Mouse Gene Knockout Kit (CRISPR)
KN516009 1 Kit

Slc26a7 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
NTAQ1 (NM_001283027) Human Tagged ORF Clone
RG235953 10 µg

NTAQ1 (NM_001283027) Human Tagged ORF Clone

Sign In for Pricing
View Details